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James Harrison, credited with saving 2.4 million babies via blood plasma donations, dies at 88

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March 5, 2025
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James Harrison, credited with saving 2.4 million babies via blood plasma donations, dies at 88
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Melbourne, Australia — An Australian man credited with saving 2.4 million babies through his record-breaking blood plasma donations over six decades, has died, his family said Tuesday. He was 88.

James Harrison, a retired state railway department clerk, died in a nursing home on the central coast of New South Wales state on Feb. 17, according to his grandson, Jarrod Mellowship.

In this May, 2011, photo provided by Australian Red Cross Lifeblood, donor James Harrison, credited with saving 2.4 million babies through his record-breaking blood plasma donations over six decades, is seen giving blood at donation center in Sydney.

Australian Red Cross Lifeblood via AP


Harrison’s plasma contained a rare antibody known as anti-D. It’s used to make injections that protect unborn babies from hemolytic disease of the newborn, in which a pregnant woman’s immune system attacks her fetus’ red blood cells. The disease is most common when a woman has an Rh-negative blood type and her baby’s is Rh-positive.

Australia has only 200 anti-D donors. They help 45,000 mothers and their babies annually.

Despite an aversion to needles, Harrison made 1,173 donations after he turned 18 in 1954 until he was forced to retire in 2018, at the age of 81.

“He did it for the right reasons. As humble as he was, he did like the attention. But he would never do it for the attention,” Mellowship said, adding his grandfather had been surprised to be recognized by Guinness World Records in 2005 as the person who had donated the most blood plasma in the world.

The record was beaten in 2022 by American Brett Cooper from Walker, Michigan.

Australian blood service pays tribute to James Harrison  

The Australian Red Cross Blood Service said Harrison was renowned as the “Man with the Golden Arm.” That national agency, which is responsible for collecting and distributing blood products, is also known as Lifeblood.

Its chief executive, Stephen Cornelissen, said Harrison had hoped that someone in Australia would one day beat his donation record.

“James was a remarkable, stoically kind and generous person who was committed to a lifetime of giving, and he captured the hearts of many people around the world,” Cornelissen said in a statement.

“It was James’ belief that his donations were no more important than any other donors’ and that everyone can be special in the same way that he was,” Cornelissen added.

Lifeblood said that, “It’s with enormous gratitude that we acknowledge the generous life of James Harrison. … We thank James for the incredible contribution he made and the millions of lives he has saved.”

Mellowship said his mother, Tracey Mellowship, Harrison’s daughter, needed the treatment when he and his brother, Scott, were born.

Jarrod Mellowship said his own wife, Rebecca, also needed the treatment when three of their four children were born.

How James Harrison’s blood might have acquired its unique feature

There is speculation that Harrison developed high concentrations of anti-D as a result of his own blood transfusions during major lung surgery when he was 14.

“After the surgery, his dad, Reg, told grandad you’re only really alive because people donated blood,” Jarrod Mellowship said. “The day he turned 18, he started donating.”

The application of anti-D in fighting hemolytic disease of the newborn wasn’t discovered until the 1960s.

Harrison, who was born in New South Wales, is survived by his sister, Margaret Thrift, his daughter, two grandsons and four great-grandchildren.

More from CBS News

Tags: BabiesbloodBlood DonationcreditedDiesDonationsHarrisonJamesMillionplasmasaving
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